Nitrogenase is a catalyst used by nitrogen-fixing microorganisms to convert atmospheric nitrogen into ammonia at ambient temperature and pressure.The structure of the active site in molybdenum nitrogenase has evolved from Fe2S2∙Mo2O2 to MoFe7S9C(R-Hhomocit)(cys)(his)(H4homocit=homocitric acid,Hcys=cysteine,Hhis=histidine)through advancements in chemical modeling,spectroscopy,and theoretical calculations,especially for structural biology.This paper provides a comprehensive review of the important achievements in the study of the active site of nitrogenase from a chemical structure perspective over the past fifty years.
关键词
固氮酶/钼铁蛋白/铁钼辅基/活性中心
Key words
Nitrogenase/MoFe-protein/FeMo-cofactor/Active site
维普
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