Selective Synthesis of Diarylmethyl Anilines and Triarylmethanes via Multicomponent Reactions:Introduce a Comprehensive Experiment of Organic Chemistry
This article presents a comprehensive organic chemistry experiment in which salicylaldehyde,phenylboronic acid,and aromatic amines are employed as the substrates.The selective synthesis of diarylmethyl aniline and triarylmethane could be achieved through the control of substituents.The structure of the product is characterized by 1H NMR and 13C NMR.This experiment combines theoretical knowledge to inspire students to think about mechanisms,helps them broaden their knowledge horizons,and establishes the concept of "green chemistry" and environmental awareness.