大学化学2024,Vol.39Issue(11) :136-145.DOI:10.3866/PKU.DXHX202401083

含氮环烷烃选择性构建功能化芳烃研究进展

Progress in Selective Construction of Functional Aromatics from Nitrogenous Cycloalkanes

张云皓 王一诺 王思然 徐大振
大学化学2024,Vol.39Issue(11) :136-145.DOI:10.3866/PKU.DXHX202401083

含氮环烷烃选择性构建功能化芳烃研究进展

Progress in Selective Construction of Functional Aromatics from Nitrogenous Cycloalkanes

张云皓 1王一诺 1王思然 1徐大振1
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作者信息

  • 1. 南开大学化学学院,农药国家工程研究中心,天津 300071
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摘要

含氮杂环类化合物广泛存在于自然界,具有多种生物活性.近几年,使用含氮环烷烃作为原料合成含氮芳烃成为目前的一个研究热点,该方法无需导向基团,可选择性地一步实现C―C、C―N、C―S和C―Se键的构建和芳构化.本文整理了近年来有关该方法构建功能化喹啉和吲哚的文献报道,进行了系统的梳理和综述,并对该领域未来的发展作出展望.

Abstract

Nitrogen-containing aromatic compounds are ubiquitous in nature.They often exhibit a wide range of biological activities.Therefore,chemists have been studying on the preparation of them for a long time as well as developing various methods for their derivatization.Recently,the direct oxidation of nonaromatic cyclicsubstrates to prepare selectively substituted aromatics has been one of research focuses.In which,the functionalized aromatics could be obtained via C―C,C―N,C―S and C―Se bonds formation without the directing groups in one step.This paper reviews the recent progress in the construction of functional quinoline and indole by this method,and proposes future development prospects in this field.

关键词

吲哚/喹啉/去氢化/芳构化

Key words

Indole/Quinoline/Dehydrogenation/Aromatization

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出版年

2024
大学化学
北京大学 中国化学会

大学化学

影响因子:0.636
ISSN:1000-8438
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