Axially chiral compounds possess unique chiral structures and have significant applications across diverse fields such as asymmetric catalysis,pharmaceuticals,optoelectronic materials,and natural products.In recent years,substantial advancements have been achieved in the enantioselective synthesis of these compounds.Beyond the conventional C―C and C―N axial chiral compounds,notable breakthroughs have been realized in the asymmetric synthesis of chiral compounds featuring N―N,C―S,C―O,and C―B axes.This review summarizes the recent progress in the asymmetric synthesis of various axially chiral compounds and discusses future directions in this research area.
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