新型冠状病毒感染对癫痫发作的影响及机制研究进展
Research progress on the influence and mechanism of SARS-CoV-2 infection on seizure
向淇 1刘学伍1
作者信息
- 1. 山东第一医科大学附属省立医院·山东省立医院神经内科(济南 250021);山东大学癫痫病学研究所(济南 250021)
- 折叠
摘要
目前,癫痫患者(Patients with epilepsy,PWE)与严重急性呼吸综合征冠状病毒-2(Severe acute respiratory syndrome coronavirus-2,SARS-CoV-2)的研究稀少且多项研究结果不一致.SARS-CoV-2可能通过多种机制导致新发癫痫发作,PWE对SARS-CoV-2的易感性及死亡率尚存在争议.在SARS-CoV-2大流行期间,癫痫患者普遍存在焦虑抑郁等各种心理问题,临床医生提供远程医疗、电话聊天及视频通话等可以有效降低PWE患者发生心理障碍的风险.同时抗癫痫发作药物与各种抗病毒药物之间存在许多相互作用,在使用时应谨慎考虑.考虑到研究结果较少且多项研究相互矛盾,PWE与SARS-CoV-2值得在未来的研究中继续探索.
Abstract
At present,there are few studies on patients with epilepsy(PWE)and severe acute respiratory syndrome coronavirus-2(SARS-CoV-2),and the results of many studies are inconsistent.SARS-CoV-2 may cause new seizures through a variety of mechanisms,and the susceptibility and mortality of PWE to SARS-CoV-2 remains controversial.During the SARS-CoV-2 pandemic,anxiety,depression and other psychological problems were common among epileptic patients.Clinicians providing telemedicine,telephone chat and video call can effectively reduce the risk of psychological disorders in PWE patients.At the same time,there are many interactions between antiepileptic drugs and various antiviral drugs,which should be carefully considered when using.Considering that the research results are few and many studies contradict each other,PWE and SARS-CoV-2 deserve further exploration in future studies.
关键词
严重急性呼吸综合征冠状病毒-2/新型冠状病毒疾病/癫痫/癫痫发作Key words
Severe acute respiratory syndrome coronavirus-2/Corona virus disease 2019/Epilepsy/Seizure引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据