Respiratory complications of propofol,sevoflurane,and dexmedetomidine anesthesia for fiberoptic bronchoscopy in children aged 1 month to 3 years:a randomized trial

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外文标题：Respiratory complications of propofol,sevoflurane,and dexmedetomidine anesthesia for fiberoptic bronchoscopy in children aged 1 month to 3 years:a randomized trial

外文摘要：Objective To evaluate the effect of propofol,sevoflurane,and dexmedetomidine on respiratory complications in children undergoing fiberoptic bronchoscopy(FOB).Methods This double-blind randomized clinical trial was conducted among 120 children aged 1 month to 3 years undergoing FOB.The patients were randomized into 3 groups(n=40)for anesthesia induction with sevoflurane inhalation,1 mg/kg propofol,or 1 µg/kg dexmedetomidine before bronchoscopy,and the changes in hemodynamic parameters,sedation level,and respiratory complications during and after the procedure were assessed.Results The patients'heart rate during bronchoscopy was significantly lower and the mean arterial blood pressure significantly higher in dexmedetomidine group than in sevoflurane and propofol groups(P<0.05).Cough during bronchoscopy did not occur in any of the cases in propofol group,while the highest frequency of cough was recorded in dexmedetomidine group.The incidence of laryngospasm in the propofol group(12.5%)was significantly lower than those in sevoflurane and dexmedetomidine groups(30%and 32.5%,respectively)(P<0.05).Conclusion Sevoflurane and propofol are safe and suitable for anesthesia induction in children below 3 years of age undergoing diagnostic FOB and can achieve better sedative effect and lower the incidences of cough and respiratory complications as compared with dexmedetomidine.

外文关键词：

fiberoptic bronchoscopypropofolsevofluranedexmedetomidinechildren

作者：

Amir Shafa、Mohammad Montasery、Sedighe Shahhosseini、Majid Keivanfar、Asieh Maghami Mehr、Mahtab Ebrahim Babaei、Mohammad Jafari

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作者单位：

Department of Anesthesiology,Isfahan University of Medical Sciences,Isfahan,Iran

Anesthesiology and Critical Care Research Center,Isfahan University of Medical Sciences,Isfahan,Iran

Department of Pediatrics,Isfahan University of Medical Sciences,Isfahan,Iran

Department of Statistics,Yazd University,Yazd,Iran

Departments of Obstetrics and Gynecology,Shahrekord University of Medical Sciences,Shahrekord,Iran

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关键词：

fiberoptic bronchoscopy propofol sevoflurane dexmedetomidine children

出版年：

2024

DOI：

10.12122/j.issn.1673-4254.2024.09.01

南方医科大学学报

南方医科大学

南方医科大学学报

CSTPCD北大核心

影响因子：1.654

ISSN：1673-4254

年,卷(期)：2024.44(9)