中国耳鼻咽喉头颈外科2024,Vol.31Issue(1) :26-30.DOI:10.16066/j.1672-7002.2024.01.006

2019新型冠状病毒变异株奥密克戎感染后嗅觉、味觉和听觉障碍的发病率和预后:一项基于网络的调查

Incidence and prognosis of olfactory,gustatory and auditory dysfunctions related to infection of COVID-19 Omicron strain:A network-based survey

王霖露 文译辉 李健 钟华 文卫平
中国耳鼻咽喉头颈外科2024,Vol.31Issue(1) :26-30.DOI:10.16066/j.1672-7002.2024.01.006

2019新型冠状病毒变异株奥密克戎感染后嗅觉、味觉和听觉障碍的发病率和预后:一项基于网络的调查

Incidence and prognosis of olfactory,gustatory and auditory dysfunctions related to infection of COVID-19 Omicron strain:A network-based survey

王霖露 1文译辉 1李健 1钟华 1文卫平1
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作者信息

  • 1. 中山大学附属第一医院耳鼻咽喉科,中山大学耳鼻咽喉科学研究所,广州市耳鼻咽喉科学重点实验室,广东 广州 510080
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摘要

目的 了解2019新型冠状病毒变异株奥密克戎(Omicron)感染后嗅觉、味觉及听觉障碍发病率及预后.方法 基于线上问卷的横断面研究,采用视觉模拟量表(VAS)评价嗅觉、味觉及听觉功能.结果(1)共获得869份有效调查问卷,Omicron感染后耳鼻咽喉科相关症状总体发生率达96.8%,嗅觉、味觉及听觉障碍发生率分别为44.4%、44.2%和10.7%.(2)全体受调查者感染前后嗅觉、味觉、听觉障碍VAS评分,及出现嗅觉、味觉及听觉障碍的受调查者感染前后相应VAS评分均具有统计学差异(P<0.001).(3)嗅觉、味觉及听觉障碍持续的中位时间分别为5 d、4 d和3 d.结论 Omicron感染后嗅觉、味觉、听觉障碍发生率高,多数可快速自发改善,对于症状长期存在者,耳鼻咽喉科医师需积极干预.

Abstract

OBJECTIVE To determine the incidence and prognosis of olfactory,gustatory and auditory dysfunctions related to the COVID-19 Omicron strain infection.METHODS A cross-sectional investigation was performed through online questionnaires.Data of patients with Omicron strain infection from December 24th,2022 to January 2nd,2023 were collected.The visual analogue scale(VAS)was used to evaluate the self-reported olfactory,gustatory and auditory functions of patients.RESULTS A total of 869 valid questionnaires were obtained.The incidence of otolaryngology-related symptoms associated with omicron strain infection was 96.8%.The incidence of olfactory,gustatory and auditory dysfunction was 44.4%,44.2%and 10.7%,respectively.There were statistically significant differences(P<0.001)in VAS scores for olfactory,gustatory,and auditory impairments between all surveyed individuals before and after infection,as well as in the corresponding VAS scores for those who experienced these impairments.The median duration of olfactory,gustatory and auditory dysfunction were 5,4 and 3 days,respectively.CONCLUSION The incidence of olfactory,gustatory,and auditory impairments is high after Omicron infection,with most cases experiencing rapid spontaneous improvement.For the long-term symptoms,the otolaryngology doctors are responsible for exploring and developing effective intervention measures.

关键词

嗅觉障碍/味觉障碍/听觉障碍/发病率/预后/新型冠状病毒

Key words

Olfaction Disorders/Taste Disorders/Auditory Perceptual Disorders/Incidence/Prognosis/COVID-19

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基金项目

国家自然科学基金(81900923)

广东省基础与应用基础研究基金(2020A1515010901)

广东省基础与应用基础研究基金(2023A1515010664)

广州市科技计划(202102020763)

出版年

2024
中国耳鼻咽喉头颈外科
中国医疗保健国际交流促进会 北京市耳鼻咽喉科研究所

中国耳鼻咽喉头颈外科

CSTPCDCSCD
影响因子:0.667
ISSN:1672-7002
参考文献量25
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