摘要
目的 探讨改变生活及饮食方式在咽喉反流性疾病(LPRD)治疗中的疗效.方法 选取2022年1月～2023年6月于福建医科大学附属第二医院门诊治疗的92例LRPD患者作为研究对象,分为对照组46例和治疗组46例.对照组采用常规的抑酸及促胃动力治疗,治疗组在对照组治疗基础上,给予生活及饮食方式指导.比较治疗后8周、12周两组的反流症状指数(RSI)量表、反流体征评分(RFS)量表各项指标变化及临床疗效.结果 RSI总分治疗后8周与治疗前比较,对照组和治疗组均较治疗前有改善(P＜0.05);RSI总分治疗后12周与治疗后8周比较,对照组和治疗组均较治疗前有改善(P＜0.05).RFS总分治疗后8周与治疗前比较,对照组和治疗组均较治疗前有改善(P＜0.05);RFS总分治疗后12周与治疗后8周比较,对照组和治疗组均较治疗前有改善(P＜0.05).治疗8周后,对照组总有效率(60.9%)与治疗组总有效率(71.7%)比较,两组比较差异无统计学意义(χ2=1.335,P=0.513).治疗12周后,对照组总有效率(73.9%)与治疗组总有效率(91.3%)比较,两组比较差异有统计学意义(χ2=6.226,P=0.044).结论 生活及饮食方式改变应成为LRPD治疗的重要一部分,通过调整不良生活饮食方式,可以明显减轻患者症状,获得更好的临床疗效.
Abstract
OBJECTIVE To explore the effect of changing lifestyle diet in the treatment of laryngeal reflux disease(LRPD).METHODS A total of 92 patients with LRPD who received outpatient treatment in the Second Affiliated Hospital of Fujian Medical University from January 2022 to June 2023 were selected as the study control,divided into control group(46 cases)and treatment group(46 cases).The control group was treated with conventional acid suppression and gastric motogenic therapy.The treatment group was treated on the basis of the control group with giving guidance on lifestyle and diet.The changes of reflux symptom index scale(RSI)and reflux sign score scale(RFS)and the clinical efficacy of the two groups were compared 8 weeks and 12 weeks after treatment.RESULTS RSI total score was improved 8 weeks after treatment compared with before treatment in both RSI control group and treatment group(P＜0.05).The total RSI score of 12 weeks after treatment was improved compared with that of 8 weeks after treatment in both control and treatment groups(P＜0.05).The total RFS score at 8 weeks after treatment was improved in both control group and treatment group compared with before treatment(P＜0.05).Compared with 8 weeks after treatment,the total RFS score in both control group and treatment group was improved(P＜0.05).After 8 weeks of treatment,the total effective rate of the control group(60.9%)was compared with that of the treatment group(71.7%),and there was no significant difference between the two groups(χ2=1.335,P=0.513).After 12 weeks of treatment,the total effective rate of the control group(73.9%)was compared with the total effective rate of the treatment group(91.3%),and the difference between the two groups was statistically significant(χ2=6.226,P=0.044).CONCLUSION The change of lifestyle and diet should become an important part of the treatment of LRPD.By adjusting the unhealthy lifestyle and diet,the symptoms of patients can be significantly reduced and better clinical efficacy can be obtained.
基金项目
福建省卫生健康委科技项目(2021TG01010013)
国家科技期刊平台
NSTL
维普
万方数据