中国耳鼻咽喉头颈外科2024,Vol.31Issue(8) :485-491.DOI:10.16066/j.1672-7002.2024.08.002

甲状腺癌患者术后早期症状群与生活质量的相关性研究

Correlation between early postoperative symptom groups and quality of life in patients with thyroid cancer

李妍 孙琳 武梦晓 寇翠敏 李正江 范改萍 李霞 尹楠 吕青
中国耳鼻咽喉头颈外科2024,Vol.31Issue(8) :485-491.DOI:10.16066/j.1672-7002.2024.08.002

甲状腺癌患者术后早期症状群与生活质量的相关性研究

Correlation between early postoperative symptom groups and quality of life in patients with thyroid cancer

李妍 1孙琳 1武梦晓 1寇翠敏 1李正江 1范改萍 2李霞 2尹楠 1吕青1
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作者信息

  • 1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院头颈外科,北京 100021
  • 2. 中国医学科学院肿瘤医院山西医院头颈外科,山西 太原 030013
  • 折叠

摘要

目的 研究甲状腺癌患者术后早期症状群和生活质量,探讨两者的相关性.方法 2023年7月~2023年10月,采用方便抽样法抽取中国医学科学院北京协和医学院肿瘤医院和中国医学科学院北京协和医学院肿瘤医院山西医院头颈外科甲状腺癌术后1~3 d患者为调查对象,采用一般资料调查表、甲状腺癌生命质量量表(EORTC QLQ-THY34)以及生活质量核心问卷(EORTC QLQ-C30)进行调查.采用探索因子提取甲状腺癌患者术后的早期症状群,调查生活质量得分,并进行Pearson相关分析,探讨两者相关性.结果 因子分析法提取4个症状群分别为咽喉-嗓音症状群、肢体麻木-情绪症状群、吞咽相关症状群和躯体应激症状群,累计方差贡献率为64.93%;甲状腺癌术后早期患者的总体健康状况评分为5.12±1.65,低于正常水平,其中功能领域中得分由高到低依次为认知功能评分(3.74±0.45)、情绪功能评分(3.21±0.43)、社会功能(2.96±0.76)、角色功能(2.66±0.73);症状领域得分最高的为疲倦(1.77±0.39)、疼痛(1.75±0.50);症状群评分与生活质量各维度得分呈负相关(P<0.05),各个症状群与生活质量各维度均具有显著相关性,咽喉-嗓音症状群与睡眠障碍及角色功能相关性最强(r=0.646、-0.561),肢体麻木-情绪症状群与社会功能和失眠、总体健康状况最相关(r=-0.538、0.529、-0.529),吞咽异常症状群与躯体功能、睡眠障碍和疲倦最相关(r=-0.491、0.491、0.476),躯体应激症状群与躯体功能和疲倦最相关(r=-0.523、-0.520),睡眠障碍与各症状群均有较强的相关性强(r>0.400).结论 甲状腺癌患者术后早期存在4个症状群,影响患者术后的生活质量,医护人员应及时评估、识别术后患者相关症状及症状群,进行有效管理,以提高患者术后的生活质量,促进康复.

Abstract

OBJECTIVE To study the correlation between the early postoperative symptom groups and quality of life in patients with thyroid cancer. METHODS From July 2023 to October 2023,patients after thyroid cancer at 1 to 3 days in Beijing and Shanxi Hospitals were selected,and the general data questionnaire,thyroid cancer quality of life scale(EORTC QLQ-THY 34) and quality of life core questionnaire(EORTC QLQ-C30) were used. Exploration factors were used to extract the early symptom group of thyroid cancer patients,investigate the scores of the quality of life,and conduct Pearson correlation analysis. RESULTS Factor analysis extracted four symptom groups:throat-voice symptom group,limb numbness-emotional symptom group,swallowing related symptom group,physical stress symptom group,The cumulative variance contribution rate was 64.93%. The overall health status score of patients with thyroid cancer in the early postoperative stage was 5.12±1.65,it was below the normal level. In the functional domain,the cognitive function score was 3.74±0.45,emotional function score 3.21±0.43,social function 2.96±0.76,and role function 2.66±0.73. The highest scores in the symptom domain were fatigue 1.77±0.39 and pain 1.75±0.50. The symptom group scores were negatively correlated with the scores of all dimensions of quality of life(P<0.05). Each symptom group and each dimension of the quality of life showed significant correlation. The throat-voice symptom group had the strongest correlation with sleep disturbance and role function(r=0.646,r=-0.561). Limb numbness-emotional symptom group was most associated with social functioning,insomnia,and general health(r=-0.538,r=0.529,r=-0.529). Groups of abnormal swallowing symptoms were most associated with physical function,sleep disturbance,and fatigue(r=-0.491,r=0.491,r=0.476),Groups of physical stress symptoms were most associated with physical function and fatigue(r=-0.523,r=-0.520). Sleep disorder had strong associations with each symptom group(r>0.400). CONCLUSION There are four symptom groups in thyroid cancer patients in the early postoperative period,which affect the quality of life of the patients after surgery. Medical staff should timely evaluate and identify the relevant symptoms of the patients after surgery,and conduct effective management,so as to improve the quality of life of the patients after surgery and promote recovery.

关键词

甲状腺肿瘤/生活质量/手术后/症状群/相关性

Key words

Thyroid Neoplasms/Quality of Life/Postoperative/symptom group/correlation

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基金项目

国家自然科学基金面上项目(82373439)

出版年

2024
中国耳鼻咽喉头颈外科
中国医疗保健国际交流促进会 北京市耳鼻咽喉科研究所

中国耳鼻咽喉头颈外科

CSTPCD
影响因子:0.667
ISSN:1672-7002
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