Recent diagnostic and therapeutic advances of retroperitoneal infection in duodenal perforation after endoscopic retrograde cholangiopancreatography
Duodenal perforation is an occasional and yet serious complication of endoscopic retrograde cholangiopancreatography(ERCP)and sphincterotomy.Its early clinical symptoms are often difficult to differentiate with those of postoperative pancreatitis and cholangitis.Delayed diagnosis and retroperitoneal infection may lead to sepsis and multiple organ failure with prolonged hospitalization and higher mortality.Loose intraperitoneal tissue easily spreads along retroperitoneal space and poor blood supply causes early abscess formation.An early diagnosis and timely interventions shall greatly improve patient outcomes.This review summarized the domestic and foreign literature on properly managing retroperitoneal infection in duodenal perforation after ERCP.