Efficacy of Hassab operation based upon hemodynamic characteristics in portal hypertension
Objective To explore whether or not Hassab operation can effectively improve hepatic artery perfusion and liver function in patients with decompensated cirrhosis.Methods A total of 97 patients with hepatitis B cirrhosis and portal hypertension hypersplenism undergoing Hassab operation were selected and divided into two groups of disease(n=40)and control(n=57)according to the diagnostic criteria of splenic artery steal syndrome(SASS).The inter-group differences in perioperative parameters were compared.Results No significant inter-group differences existed in perioperative parameters(P>0.05)or model for end-stage liver disease(MELD)score at Day 3 post-operation(P>0.05).At Day 7 post-operation,MELD score of SASS group was significantly better than that of control group[(3.17±2.96)vs.(4.68±2.31)];At Day 14 post-operation,the values of hepatic artery diameter/velocity were significantly better in SASS group than those in control group[(4.13±0.33)vs.(3.85±0.34)mm;(50.83±3.85)vs.(47.55±3.05)cm/s](P<0.05).Conclusion Hassab operation can effectively improve hepatic artery perfusion and liver function in patients with decompensated cirrhosis.Introducing the concept of"Cirrhotic SASS"into clinical practices may benefit more patients with cirrhosis,portal hypertension and hypersplenism.
万方数据
维普
