Application outcomes of naso-pancreatic duct in patients with severe acute pancreatitis intraperitoneal infection complicated with pancreatic fistula
Objective To explore the application outcomes of naso-pancreatic duct in patients with intraperitoneal infection of severe acute pancreatitis complicated with pancreatic fistula.Methods From June 2019 to January 2021,the relevant clinical data were retrospectively reviewed for 47 patients with intraperitoneal infection of severe acute pancreatitis plus pancreatic fistula.They were assigned into two groups of treatment(n=22)and control(n=25).Treatment group had an insertion of a naso-pancreatic duct during endoscopic retrograde cholangiopancreatography(ERCP)while control group was not placed.Postoperative efficacy was examined.Results As compared with control group,study group underwent nasal pancreatic duct drainage via ERCP for(12.10±5.89)days.And indwelling time of control group was(17.90±3.95)days.Abdominal drain had markedly reduced indwelling time,And sepsis during treatment occurred at a rate of 4.5%(1/22)in study group and a rate of 32.0%(8/25)in control group.The incidence of active abdominal hemorrhage requiring intervention or surgical intervention was 4.5%(1/22)in study group and 28.0%(7/25)in control group.And pseudocysts occurred at a rate of 13.6%(3/22)in study group and a rate of 40.0%(10/25)in control group.All differences were statistically significant(all P<0.05),However,no significant difference existed in duration of leucocytosis or length of hospitalization(P>0.05).Conclusion For patients with severe intraperitoneal infection of acute pancreatitis complicated with pancreatic fistula,naso-pancreatic duct implantation may minimize the amount of pancreatic fistula and control abdominal infection,thereby arresting the progression of the disease to refractory pancreatic fistula and the occurrence of serious complications such as pancreatic pseudocyst and massive bleeding.It can reduce the time of patients with tube,and its application has certain clinical value.
Severe acute pancreatitisIntraperitoneal infectionPancreatic fistulaNaso-pancreatic ductEndoscopic retrograde cholangiopancreatography
万方数据
维普
