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改良Kakita胰肠吻合技术在胰十二指肠切除术中的应用

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目的 探讨改良Kakita胰肠吻合技术(pancreaticojejunostomy,PJ)在胰十二指肠切除术(pancreaticoduodenectomy,PD)中的应用效果.方法 选取2018年5月至2022年6月期间于武汉大学中南医院等5家医院采用改良Kakita PJ进行PD的病人,其中将153例行开腹PJ的病人分为A组,将110例行微创PJ的病人分为B组.A组包括135例开腹胰十二指肠切除术,13例微创PD中转开腹以及5例微创PD小切口吻合病人;B组包括87例腹腔镜下胰十二指肠切除术以及23例机器人辅助胰十二指肠切除术病人.回顾性分析两组病人的围术期临床资料.结果 263例PD均顺利完成.(1)A组:PJ时间中位数为9 min(7~15 min),术中出血量中位数为200 mL(50~1 000 mL),18例(11.8%)术后并发症Clavien-Dindo分级≥3级,B、C级胰瘘14例(9.2%),胆漏8例(5.2%),B、C级腹腔内出血13例(8.5%),消化道出血1例(0.7%),腹腔内感染14例(9.2%),术后30 d内再次手术者8例(5.2%),术后90 d内死亡2例(1.3%),死亡病例均由胰瘘引起.(2)B组:PJ时间中位数为17 min(12~25 min),术中出血量中位数为60 mL(10~250 mL),7例(6.4%)术后并发症Clavien-Dindo分级≥3级,B、C级胰瘘5例(4.6%),胆漏5例(4.6%),B、C级腹腔内出血3例(2.7%),消化道出血1例(0.9%),腹腔内感染9例(8.2%),术后30 d内再次手术者3例(2.7%),术后90 d内死亡者1例(0.9%),死亡病例与胰瘘无关.结论 改良Kakita PJ操作简便,易于开展,可在开腹以及微创PD中安全实施.
Application of modified Kakita pancreaticojejunostomy during pancreaticoduodenectomy
Objective To explore the feasibility of modified Kakita pancreaticojejunostomy(PJ)during pancreaticoduodenectomy(PD).Methods Between May 2018 and June 2022,153 patients undergoing open PJ were selected as group A while 110 patients undergoing mini-invasive PJ as group B.In group A,the procedures included open pancreaticoduodenectomy(OPD,n=135),mini-invasive PD with a conversion into laparotomy(n=13)and mini-invasive PD with a small retrieval incision reconstruction(n=5).In group B,laparoscopic pancreaticoduodenectomy(LPD,n=87)and robotic pancreaticoduodenectomy(RPD,n=23).The perioperative clinical data of two groups were retrospectively reviewed.Results A total of 263 cases of PD were successfully performed.In group A,median time of PJ was 9(7-15)min and median volume of blood loss 200(50-1 000)mL.There were postoperative complication(Clavien-Dindo≥3)(n=18,11.8%),grade B/C postoperative pancreatic fistula(POPF)(n=14,9.2%)and biliary fistula(n=8,5.2%).There were grade B/C intra-abdominal hemorrhage(n=13,8.5%)and gastrointestinal hemorrhage(n=1,0.7%).Fourteen patients(9.2%)were diagnosed as intra-abdominal infection.30-day reoperation occurred in 8 patients(5.2%)and 2 patients(1.3%)died because of grade C POPF within 90 days of surgery.In group B,median time of PJ was 17(12-25)min and median volume of blood loss 60(10-250)mL.Among postoperative complication(Clavien-Dindo≥3)(n=7,6.4%),there were grade B POPF(n=5,4.6%),biliary fistula(n=5,4.6%),grade B/C intra-abdominal hemorrhage(n=3,2.7%)and gastrointestinal hemorrhage(n=1,0.9%).Nine patients(8.2%)were diagnosed as intra-abdominal infection.30-day reoperation occurred(n=3,2.7%)and 1 patient(0.9%)died within 90 days of surgery.Conclusion With a short learning curve,modified Kakita PJ may be performed under OPD or mini-invasive PD.

PancreaticoduodenectomyPancreaticojejunostomyRobotLaparoscopyPostoperative pancreatic fistula

陈志楠、赵安邦、刘志程、朱倩、秦弦、魏征、曾长江、周文富、杨潇、王帅、孙振纲、金保涛、胡凯、刘志苏、袁玉峰、杨智勇

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武汉大学中南医院肝胆胰外科,湖北 武汉 430071

武汉大学中南医院胰腺外科中心,湖北 武汉 430071

湖北省肝胆胰疾病微创诊治临床医学研究中心,湖北 武汉 430071

长江大学附属仙桃市第一人民医院肝胆外科,湖北 仙桃 433099

潜江市中心医院肝胆外科,湖北 潜江 433199

长江大学附属荆州医院肝胆外科,湖北 荆州 434020

荆州市第二人民医院普外一科,湖北 荆州 434000

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胰十二指肠切除术 胰肠吻合技术 机器人 腹腔镜 术后胰瘘

湖北省肝胆胰疾病微创诊治临床医学研究中心平台匹配经费

PTPP2021005

2024

腹部外科
中华医学会武汉分会

腹部外科

CSTPCD
影响因子:0.615
ISSN:1003-5591
年,卷(期):2024.37(1)
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