Safety and efficacy of laparoscopy-assisted pylorus-preserving gastrectomy for early middle-third gastric cancer based upon propensity score matching
Objective To evaluate the safety and efficacy of laparoscopy-assisted pylorus-preserving gastrectomy(LAPPG)for early middle-third gastric cancer(GC).Methods From January 2016 to December 2020,the relevant clinicopathological data were retrospectively reviewed for patients with early middle-third GC undergoing LAPPG.Propensity score matching was employed.Perioperative events of general profiles,tumor pathological features,intraoperative findings and postoperative recovery were recorded.At Month 6 post-operation,nutritional status and the incidence of bile reflux gastritis(BRG)were examined.Results Operative duration was slightly longer in LAPPG group than that in laparoscopy-assisted distal gastrectomy(LADG)group[(226.6±18.2)vs(220.6±18.4)min].And the incidence of BRG was lower in LAPPG group than that in LADG group(9.5%vs 33.6%).No inter-group differences existed in count of dissected lymph nodes[(20.4±6.1)vs(21.4±7.5)],postoperative hospital stay[8(6-32)vs 8(6-31)day]or recovery period.Both accorded with the diagnostic and therapeutic guidelines.Conclusion Both safe and feasible,LAPPG has demonstrated no significant difference in perioperative safety and effectiveness as compared with LADG.And LAPPG may effectively prevent the long-term complications.