Clinical characteristics of surgery for Crohn's disease complicated with intestinal perforation:a report of 25 cases
Objective This study was intended to summarize the clinical characteristics of Crohn's disease(CD)complicated with intestinal perforation and explore the efficacy of surgery.Methods From January 2000 to October 2022,25 cases of CD complicated with intestinal perforation at Affiliated Union Hospital were retrospectively reviewed.Clinical characteristics,surgical approaches and clinical follow-up data were summarized.Results Among them,males dominated(84%)with a diagnostic age of 17 to 40 years(80%).The major site of perforation was ileum(72%)and nature of lesions largely transmural(80%).Surgical approaches included laparoscopic-assisted bowel resection(52%)and multiple ileostomies(76.9%).The postoperative complication rate was 28%and infections dominated.Both preoperative and postoperative patients were prone to anemia and hypoproteinemia.During follow-ups,there were recurrence(n=12,48%)and death(n=1).Conclusion CD complicated with intestinal perforation is more common in males and perforation occurs predominantly in ileum.Emergency surgery is recommended for all patients upon admission.Timely identification of etiology,optimal perioperative management and appropriate selection of surgical procedures may lower the incidence of postoperative complications and recurrence.
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