Effect of sarcopenic obesity on efficacy of laparoscopic sleeve gastrectomy for short-term weight loss
Objective To explore the effect of sarcopenic obesity(SO)on efficacy of laparoscopic sleeve gastrectomy(LSG)for weight reduction and examine the influencing factors for successful postoperative weight reduction.Methods From May 2020 to September 2023,retrospective analysis was performed for the relevant clinical data of 104 obese patients undergoing LSG.They were assigned into two groups of SO(n=34)and non-sarcopenic obesity(NSO,n=70).SO was diagnosed on the basis of preoperative third lumbar spine on computed tomography(CT)with a ratio of fat mass to defatted mass of not less than 0.8.The effects of SO on efficacy of LSG were analyzed comparatively and the risk factors for successful postoperative weight loss examined by unifactorial and multifactorial analyses.Results As compared with NSO patients,preoperative baseline data indicated that mean values of preoperative body mass index(BMI)and subcutaneous fat area were greater in SO patients and there was a greater percentage of patients with degree Ⅲ obesity.However,mean values of desiccated mass and skeletal muscle area were smaller.And the differences were statistically significant(P＜0.001).Postoperative follow-up data showed that mean values of postoperative BMI and excess BMI were greater in SO patients.However,mean values of percent excess weight loss and success rate of weight loss were lower and the differences were statistically significant(P＜0.05).Multivariate analyses revealed that BMI and diabetes mellitus were two independent risk factors for successful postoperative weight loss.Conclusion LSG is less effective for weight loss in SO patients.And DM and BMI are two independent risk factors for successful postoperative weight reduction.
Sarcopenic obesityLaparoscopic sleeve gastrectomyWeight loss efficacy
万方数据
维普
