Analysis of risk factors correlated with acute appendicitis with perforation
Objective To explore the risk factors of acute appendicitis(AA)with perforation.Methods From January to June 2023,a total of 212 hospitalized AA patients were selected as study subjects.According to the observation of appendix and pathological results,they were assigned into two groups of non-perforated(n=169)and perforated(n=43).Demographic profiles(e.g.gender,age &duration of onset),blood test parameters(e.g.blood routine,total bilirubin & D-dimer)and imaging findings(whether or not fecalith within appendix and ascites in abdominal cavity)were compared between two groups.The influencing factors of perforated AA were examined by multivariate Logistic regression analysis and receiver operating characteristic(ROC)curve.Results There were 43 cases of perforated A A with a perforation rate of 20.3％.Longer symptomatic duration,fever(axillary temperature ≥38 ℃),appendiceal fecalith on imaging,ascites on imaging and elevated level of C-reactive protein(CRP)were independent risk factors for perforated AA were examined by single factor and multiple factor Logistic regression(P＜0.05).The area under the ROC curve of longer symptomatic duration,ascites and CRP level were 0.827,0.853 and 0.810(P＜0.05).When all parameters were combined for prediction,AUC was 0.962 with a sensitivity of 0.884 and a specificity of 0.893.Conclusion Longer symptomatic duration,fever(axillary temperature ≥38 ℃),appendiceal fecalith on imaging,ascites on imaging and elevated CRP level are independent risk factors for perforated AA.There is a higher value when all parameters are combined for assessments.
万方数据
维普
