Evaluations of pouch function after ileal pouch-anal anastomosis
Restorative proctocolectomy with ileal pouch-anal anastomosis(IPAA)is preferred for patients with medically refractory ulcerative colitis(UC)and familial adenomatous polyposis(FAP).While many reports have discussed postoperative surgical and inflammatory complications of pouch,functional pouch disorders are poorly understood.Two complicating factors are a great variability of defining functional outcomes after IPAA and a lack of standardization for reporting symptoms.Normal pouch function has yet to be adequately defined.The underlying etiologies for poor functional outcomes are quite diverse,such as pelvic sepsis,pouchitis,anastomotic complications and pouch volvulus,etc.However,some patients manifest poor pouch function even without such complications.It is possibly due to non-optimal pouch physiology or such specific patient factors as age,gender,body mass index(BMI)and dietary habits.Therefore it is imperative to explore the normal physiological function of pouch and better manage the functional complications to enhance the postoperative quality-of-life.
万方数据
维普
