UIO-66-OH was used for the sensitive detection of amino small molecule peptides in Periplaneta Americana by SALDI-MS
A new method for the determination of amino small molecule peptides of Periplaneta Americana was established.The amino small molecule peptides of Periplaneta Americana without background interference were successfully detected by comparing with traditional substrates using only metal-organic framework material UIO-66-OH.In this study,a new method was developed for rapid detection of amino small molecule peptides in Periplaneta Americana using surface-assist-ed laser desorption ionization-mass spectrometry(SALDI-MS).Since UIO-66-OH can eliminate the interference of endog-enous macromolecules in biological samples and has a strong enrichment effect on the amino small molecule peptide LTAP-GL-NH2 of Periattella Americana,the UIO-66-OH-SALDL-MS method has been successfully applied to the determina-tion of LTAPGL-NH2 in actual plasma samples.
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