Significance of MRI in the differential diagnosis of primary central nervous system lymphoma and demyelinafing pseudotumors of brain
Objective To investigate the imaging findings of magnetic resonance imaging(MRI)in the diagnosis of de-myelinating pseudotumor and lymphoma of central nervous system,and to improve the correct diagnosis rate of the disease.Methods A retrospective analysis of 41 patients with central nervous system lymphoma and 30 patients with demyelinating pseudotumor was carried out.MRI was performed on these patients and the imaging features were summarized.Results There was no statistically significant difference in age,sex,and clinical symptoms(P＞0.05).The MRI findings that showed statis-tical significance between the two groups included the maximum diameter,diffusion weighted imaging(DWI)combined with apparent diffusion coefficient(ADC),sensitive weighted imaging(SWI).Primary central nervous system lymphoma:MRI im-aging features showed uniform enhancement characteristics after scan enhancement,manifested as"incision"and"angular".And MRS showed highly elevated lipid peak and inverted lactic acid peak.Demyelinating pseudotumors:The lesions had round or no enhancement on MRI scan.And MRS showed no specificity.Conclusion The PCNSL group had a higher incidence of dif-fusion-limited and reducing SWI signal than patients with DPTs,which is of great value in improving the diagnostic accuracy of PCNSL and DPTs.Enhanced scanning and MRS also have diagnostic value in the two groups.
magnetic resonance imaging(MRI)central nervous systemdemyelinating pseudotumorlymphomadiffer-ential diagnosis
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