Predictive value of initial serum albumin levels for in-hospital mortality in adults with aspiration pneumonia
Objective To explore the predictive value of serum albumin for in-hospital mortality in adults with aspiration pneumonia.Methods The data of adult inhalation pneumonia inpatients in the 73rd Army Group Hospital of the PLA Army o-ver the past four years were collected using a retrospective cohort study method,the impact of initial serum albumin levels in mergency departments on in-hospital mortality in patients with aspiration pneumonia was assessed,and its correlation with in-hospital mortality was analyze.Results A total of 248 patients were enrolled,of whom,51 patients(20.6％)died.The mean serum albumin level was(3.4±0.7)g/dL.The serum albumin level was significantly lower in the non-survivor group than that in the survivor group[(3.0±0.6)g/dL vs.(3.5±0.6)g/dL].In the multivariable logistic regression model,albumin was as-sociated with in-hospital mortality significantly.The area under the receiver operating characteristics(AUROC)for predicting in-hospital mortality using serum albumin was 0.72[95％CI(0.64,0.80)].The Youden index was 35.10％,and the corre-sponding sensitivity,specificity,positive predictive value,negative predictive value,positive and negative likelihood ratio was 68.6％,66.5％,34.7％,89.1％,2.05 and 0.47,respectively.Highest sensitivity(98.0％)was shown at albumin level of 4.0 g/dL and highest specificity(94.9％)was shown at albumin level of 2.5 g/dL.Conclusion Initial serum albumin level is nega-tively correlated with in-hospital mortality among adult patients hospitalized with aspiration pneumonia,which is of great signifi-cance for clinical physicians to predict in-hospital mortality of adult aspiration pneumonia and provide a certain reference to judge the prognosis of this disease.
万方数据
维普
