Conventional magnetic resonance combined with multimodal magnetic resonance imaging for differential diagnosis of demyelinating pseudotumor and glioma
Objective To explore the value of conventional magnetic resonance imaging(MRI)and multimodal MRI in the diagnosis of demyelinating pseudotumor,and to analyze the key points of differential diagnosis between demyelinating pseud-otumor and glioma.Methods The clinical data,conventional MRI and multimodal MRI of 61 patients with demyelinating pseud-otumor and 66 patients with glioma admitted to our hospital were analyzed retrospectively,and the value of imaging signs and imaging parameters for disease diagnosis was evaluated.Results Demyelinating pseudotumors were more common in young women,and the clinical course was generally slow,with more symptoms such as ataxia and dyskinesia and less epilepsy.On the image,the occupying effect of demyelinating pseudotumor was generally light,and it was easy to show signs such as open ring enhancement,central venous sign and lateral ventricular vertical sign.Lesions on diffusion-weighted imaging(DWI)generally appeared unrestricted/diffuse restriction or open-loop diffuse restriction;The Cho/NAA and Cho/Cr values of demyelinating pseudotumors on magnetic resonance spectroscopy(MRS)were usually not high,and the NAA/Cr ratio was greater than that of gliomas.MRI images of gliomas showed that the proportion of cerebral cortex involvement(80.3％)were greater than that of demyelinating pseudotumor(31.1％).Glioma DWI was often characterized by closed-loop enhancement;57.6％of gliomas had central nodular diffusion restriction;MRS showed that seven cases of demyelinating pseudotumors showed hypoperfusion,only one case showed hyperperfusion,and all gliomas showed hyperperfusion.Conclusion Conventional MRI and multimodal MRI have certain value in the differential diagnosis of demyelinating pseudotumor and glioma.
万方数据
维普
