Association between C-peptide level and 10-year risk of ASCVD in patients with newly diagnosed type 2 diabetes mellitus
Objective To analyze the impact of serum C-peptide levels in patients with newly diagnosed type 2 diabetes(T2DM)on the 10-year risk of atherosclerotic cardiovascular disease(ASCVD).Methods A total of 345 patients with newly diagnosed T2DM were selected and categorized into four groups based on fasting C-peptide(FCP)level quartiles.The China-PAR model was employed to evaluate the 10-year ASCVD risk.Results Elevated FCP levels(greater than 0.980 ng/ml)were found to be associated with an increased 10-year ASCVD risk with this relationship being moderated by gender and weight.Mul-tiple linear regression analysis indicated that,after adjusting confounding factors such as gender,age,BMI,and glycosylated he-moglobin,FCP levels remained a positive predictor of 10-year ASCVD risk.Conclusion High FCP levels constitute a significant risk factor for future ASCVD in patients with newly diagnosed T2DM.
万方数据
维普
