首页|基于三维电阻抗层析成像的乳腺癌传感器的设计

基于三维电阻抗层析成像的乳腺癌传感器的设计

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基于三维电阻抗层析成像方法设计了一种密集型乳腺阵列传感器,并开发了一种用于检测乳腺癌的电阻抗成像传感器.此传感器采用激励电极阵列与接地电极一体化的设计实现了结构简化,并通过锥形基体与双层周向排布的电极阵列实现了电场密集化以及锥度优化,提高了目标物的检测精度.设计了成像系统,采用数值仿真方法对传感器进行优化.仿真结果表明,电极数量减半并不会影响传感器的成像精度,反而可以提高成像速度.最后,考察了传感器的性能,结果表明,系统信噪比与通道一致性良好.利用此传感器对检测场域相对体积为0.4%的实验模型进行了三维图像重建,单目标成像的图像相关系数达到0.6以上,可清晰判别双目标物位置,实现了对乳腺癌的可视化检测.
A Sensor for Detection of Breast Tumor with Three-dimensional Electrical Impedance Tomography
An intensive breast array sensor was designed based on three-dimensional electrical impedance tomography in this work.Firstly,an electrical impedance sensor for detection of breast cancer was developed.The sensor adopted the integrated design of excitation electrode array and ground electrode to achieve structural simplification.It realized electric field densification through conical matrix and double-layer circumferentially arranged electrode array and improved the detection accuracy of target object through taper optimization.Secondly,the imaging system was designed,and the sensor was optimized by numerical simulation.The simulation results showed that halving the number of electrodes did not affect imaging accuracy of the sensor,but could improve the imaging speed.Finally,the performance of the sensor was verified by experiment.The signal-to-noise ratio and channel consistency of the system were at a good level.The sensor was used to reconstruct three-dimensional image of the experimental model with relative volume of the detection field of 0.4%.The image correlation coefficient of the single target imaging was above 0.6 and the position of the double target object could be clearly identified,and thus the visual detection of breast cancer was realized.

Electrical impedance tomographySensorBreast tumorNumerical simulation

刘凯、李安琪、李芳、朱程君、田航、姚佳烽

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南京航空航天大学机电学院,南京 210016

三江学院机械与电气工程学院,南京 210012

南京医科大学第一附属医院肿瘤科,南京 210029

广州医科大学附属妇女儿童医疗中心,广州 510623

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电阻抗层析成像 传感器 乳腺癌 数值仿真

研究生科研与实践创新计划项目国家自然科学基金项目广东省基础与应用基础研究基金项目江苏省自然科学基金项目

xcxjh20230503620712242022A1515220154BK20221480

2024

分析化学
中国化学会 中国科学院长春应用化学研究所

分析化学

CSTPCD北大核心
影响因子:1.423
ISSN:0253-3820
年,卷(期):2024.52(2)
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