Electrokinetic Separation/Concentration-Signal Amplification All-in-One Strategy for Accurate Detection of Pesticide Residues
Surface-enhanced Raman scattering(SERS)is a kind of highly sensitive analytical technique for trace amount analytes,which shows great application potential in environmental analysis and food safety.Due to the potential matrices interference,it is essential to eliminate or reduce the interference of environment factors.The strategy of integration of separation/concentration with detection is an effective way to ensure accurate detection of charged molecules in complex samples.In this study,an all-in-one strategy for simultaneous concentration and highly sensitive detection of charged pesticides was developed based on the use of a reduced graphene oxide-gold nanoparticles nanocomposite(Au-RGO)modified screen-printed carbon electrode(SPCE)and combining electrokinetic trapping and SERS detection.By virtue of the signal amplification of Au-RGO,the sensitive detection of simazine,amitrole,malathion and methyl-parathion was realized.The method had wide linear detection ranges for the four kinds of pesticides(0.001-500 μmol/L),with detection limits from 0.3 to 2.0 nmol/L.This study provided a solution for the bottleneck issues such as matrix interferences and sophisticated pretreatment procedures of traditional SERS sensor for complex media,providing a new analytical method for in-field detection of environment pollutants.
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