Research Progress of Microwave Biosensors Based on Polydimethylsiloxane Microfluidic Chips
Microwave biosensors are extensively applied in detection of food safety,environmental pollution and biomedical health.Compared to traditional optical and electrochemical sensing solutions,traditional optical and electrochemical sensor detection schemes,microwave sensing shows the advantages of high precision,strong penetration and non-contact detection.Polydimethylsiloxane(PDMS)exhibits numerous favorable characteristics in terms of integration,biocompatibility and processability.The integration of microwave biosensors with PDMS microfluidic chips allows for the full exploitation of the aforementioned advantages,thereby facilitating the provision of rapid,precise,and cost-effective detection solutions.These solutions are of considerable practical significance within the domain of biomedicine.This paper provides an overview of the fundamental characteristics and operational principles of microwave biosensors.It also offers a comprehensive account of the diverse types of microwave biosensors integrated with PDMS microfluidic chips,highlighting their respective advantages and disadvantages.Furthermore,it anticipates the challenges and potential solutions in the development of a novel generation of biosensor chip integration.This is with a view to providing a viable research and development concept for the advancement of medium and large-scale integrated-chip functional microfluidic chips in China.