Synthesis of Au Nanostars and Its Application for Glucose Detection by Surface-Enhanced Raman Scattering
Au nanostars(Au NSs)were prepared by the seed growth'method,which was used for the detection of glucose by surface-enhanced Raman spectroscopy.The structure of the prepared Au NSs was characterized by transmission electron microscopy and UV-Vis spectroscopy.The diameter of the synthesized Au NSs is about 82 nm,and it has a star structure with multi-branched tips.The enhancement effect of different morphologies of Au NSs is investigated.The results show that the synthesized Au NSs have a strong surface-enhanced Raman effect,and it is applied to glucose detection.Under the optimal detection conditions,the linear range of this method for glucose detection is 1-120μmol/L,the detection limit is 29 nmol/L,and the real sample spiking recovery is 97.5％-105.6％.This method can be used for rapid and sensitive detection of glucose in a complex matrix.
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