Significance Biomedical textiles are one of the most innovative and technologically advanced research fields in the textile industry today.Surgical sutures are one of the most used medical devices in clinical surgery,and research and development of sutures have been active worldwide.As a new generation of surgical sutures,absorbable surgical sutures are the ″darling″ of the medical community,with extremely important applications in obstetrics and gynecology,surgery,otolaryngology,ophthalmology,dentistry,and so on.Absorbable surgical sutures have become the first choice of surgeons in surgical procedures by virtue of their self-degrading,non-removable and less painful properties,and patients using absorbable surgical sutures are benefitted from having minimal visible scarring on the skin after healing,enhancing patient satisfaction.Although the development of absorbable surgical sutures is now at a relatively mature stage,many high value-added absorbable surgical sutures with excellent functionality are still in the laboratory stage and cannot be industrially produced and marketed for clinical applications.Therefore,this paper focuses on the analysis of various raw materials for preparation of absorbable surgical sutures based on the latest relevant research literature to systematically summarize the current research status of absorbable surgical sutures,promote the innovative development of absorbable surgical sutures and enhance the industrial production of absorbable surgical sutures.Progress The development of absorbable sutures and their performance requirements,the history of the development of absorbable surgical sutures from ancient times to the present day are introduced first.The development of the raw materials for their preparation from single to diversified are elaborated.The specific development history is shown,and the mainstream products on the market today are shown.In addition,the properties of absorbable surgical sutures,such as good biocompatibility and good knot strength,as well as the smoothness of the suture surface,are systematically reviewed.The four natural materials used for natural absorbable suture applications,namely catgut,collagen,chitin and alginate,are scutinised and the latest research in this area is summarized and analyzed.Four types of synthetic polymers,i.e.,polylactic acid,polyglycolic acid,polycaprolactone and polyvinyl alcohol,are reviewed for making absorbable sutures and the latest research is summarized and analyzed.The advantages and disadvantages of developing absorbable surgical sutures from various materials are systematically studied and compared,and the analysis focused on three important indicators which are the mechanical properties,degradation properties and additional antibacterial properties of absorbable sutures.The overview of antimicrobial immune novel absorbable surgical sutures is also summarized the relevant mechanisms of action is described.Finally,the article concludes with an analysis and summary of the problems of today's absorbable surgical sutures and the trends of future development.Conclusion and Prospect The paper analyzes the current status of research on surgical sutures in recent years,starting from the materials used for the preparation of absorbable sutures.The technology for the development of absorbable surgical sutures is becoming more mature,but some problems still need research attention.1)Relatively little research has been conducted on natural type of absorbable surgical sutures,and the initial catgut have disadvantages such as poor mechanical properties and tendency to trigger tissue reactions,which require further modification of the material.Chitin is commonly used as a functional coating finishing material to impart antimicrobial properties in recent years due to its excellent broad-spectrum antibacterial properties,but little research has been conducted on the preparation of sutures using chitin fibers for development.2)The development of synthetic polymeric materials has provided more possibilities for the preparation of new absorbable surgical sutures.However,the degradation cycles of various materials are different,resulting in a mismatch between wound healing time and suture degradation time,which affects wound healing.Therefore,the controlled degradation of synthetic polymers is particularly important,so the research of absorbable sutures made of synthetic polymers should be enhanced in terms of the regulation of degradation properties.3)Wound infection is a persistent problem in surgical procedures,and therefore the development of absorbable surgical sutures with excellent antimicrobial properties is the main theme in suture preparation.Tthe selection of suitable antimicrobial agents,the enhancement of antimicrobial agent loading fastness,and the long-lasting and stable action of antimicrobial agents are issues requiring future research attention.
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