摘要
为解决传统抗菌非织造用品防护性能差、制备成本高和潜在毒性大等问题,以水刺棉为基材,通过低分子质量壳聚糖改性、柠檬酸共价交联和光敏剂染整一体化负载工艺,制备了具有高效广谱、抗菌耐久、安全低毒和绿色低碳的光动力抗菌水刺棉.利用紫外/可见光分光光度计、傅里叶红外光谱仪、荧光光谱仪对光动力水刺棉的化学结构和光动力学性能进行表征,通过抗菌实验探究了不同接触时间下光动力水刺棉的抗菌性能与抗菌耐久性能.结果显示:光动力水刺棉在10 min光照下能够淬灭50％以上的1,3-二苯基异苯并呋喃,属于主导能量转移的Ⅱ型光动力机制,在15 min内杀灭99％以上的金黄色葡萄球菌,在60 min内杀灭90％以上的大肠杆菌,表明功能化的水刺棉具有优异的光动力抗菌特性;此外,光动力水刺棉经光漂白和水洗使役后仍具有显著的抗菌耐久性,均可满足生物医用材料对生物安全性的要求,具有大规模制备新一代光触媒非织造用品的应用潜力.
Abstract
Objective The traditional antibacterial nonwovens are known for their inferior contact comfort,significant potential toxicity,unsatisfactory protective performance and high preparation cost.In this study,skin-friendly spunlaced cotton was selected as the substrate which were then coated by a mixture of low molecular weight chitosan,covalently crosslinked citric acid and photosensitizers.This material is featured efficient and extensive antimicrobial,green and low pollution,stable effect and superior biosafety.Method Photodynamic antimicrobial spunlaced cotton fabric was prepared by covalent crosslinking and integration of dyeing and finishing.The chemical structure and photodynamic properties of photodynamic spunlaced cotton were characterized using UV-visible spectrophotometer,Fourier infrared spectrometer and fluorescence spectroscopy.The antimicrobial performance and durability of the photodynamic spunlaced cotton were investigated by antimicrobial experiments under different contact periods.Results The FT-IR spectra and water solubility test demonstrated the successful synthesis of chitosan guanidinium salt(GCS).The color space parameters and color depth curves confirmed that the color depth curves of the photodynamic spunlaced cotton matched the UV-visible absorption spectra of the corresponding photosensitizers,with color depth values of 3.55 and 4.72 for CHL-GCF(spunlaced cotton loaded with chitosan guanidinium salt and sodium copper chlorophyllin)and RB-GCF(spunlaced cotton loaded with chitosan guanidinium salt and rose bengal),respectively.The above results indicated that the cationic surface modified with chitosan guanidinium salt facilitated the loading of negatively charged photosensitizers.The dyeing rate and loading amount of sodium copper chlorophyllin(CHL)and rose bengal(RB)on the GCF surface were further determined by measuring the absorbance of the dye solution before and after the photosensitiser staining and the washing residual solution.The staining rates of CHL-GCF and RB-GCF reached 95.78％and 96.46％,respectively,and the loading amounts of CHL-GCF and RB-GCF after washing were 18.57 mg/g and 17.24 mg/g,respectively.The anionic photosensitiser and actionized spunlaced cotton relied on electrostatic interactions to achieve relatively excellent upstaining and loading effects under salt-free dyeing.The results demonstrated that the photodynamic spunlaced cotton killed more than 99％of S.aureus in 15 minutes and more than 90％of E.coli in 60 min,as well as less potential toxicity to cells,which met the relevant requirements for biomedical materials.Finally,the breaking elongation property,air permeability,water vapor transmissibility and UV resistance of photodynamic spunlaced cotton were investigated.Compared with NCF,the breaking strength retention rate of GCF,CHL-GCF and RB-GCF was approximately 70％.The air permeability and water vapour transmission rate of the photodynamic spunlaced cotton were reduced to 1 442.92 mm/s and 2 475.8 g/(m2,d),respectively,by approximately 15％in both cases.The UV resistance coefficients reached 32.26±1.15 and 19.78±0.48,respectively,with certain UV blocking ability.Conclusion The spunlaced cotton with photodynamic microbial inactivation effect was successfully developed by adopting spunlaced cotton as the substrate,modified by covalent cross-linking with chitosan guanidinium salt,and then loaded with the photosensitiser chlorophyll copper sodium salt or rose bengal red by salt-free dyeing method.Under the simulated sunlight conditions,the photodynamic spunlaced cotton eliminated over 99％of S.aureus in 15 min,and over 90％of E.coli in 60 min,exhibiting good efficient inactivation performance and usage durability.According to the relevant standards for testing textile physical properties and biosafety indicators,photodynamic spunlaced cotton met the corresponding performance requirements,indicating outstanding contact comfort and safety.
基金项目
福建省中央引导地方科技发展专项项目(2022L3061)
福建省省级科技创新重点项目(2022G02028)
维普
万方数据