Prenatal ultrasound imaging characteristics and clinical significance of abnormal development of the inferior vena cava
Objective To explore the value and clinical significance of prenatal ultrasound examination by summarizing the ultrasound image features of fetal inferior vena cava(IVC)development abnormalities.Methods A retrospective analysis was conducted on the ultrasound image characteristics and combined intracardiac and extracardiac abnormalities of 88 cases diagnosed with fetal IVC developmental abnormalities in our hospital from January 2018 to February 2023.Multiple tabular chi square tests were performed on the composition ratio of IVC developmental abnormalities with intracardiac and extracardiac abnormalities of different types.The Bonferroni method was used for multiple comparisons between groups.All the results with postpartum MRA,echocardiography,or autopsy results were compared.Results There were 88 fetuses with abnormal IVC development,including 18 ectopic connection of inferior vena cava(ECIVC)patients,42 left inferior vena cava(LIVC)patients and 28 double inferior vena cava(DIVC)patients.18 ECIVC fetuses showed abnormalities in both the oblique coronal and four chamber views of the chest and abdomen,with 17 cases showing abnormalities in the transverse section of the abdomen and 1 case showing atypical abnormalities in the transverse section of the abdomen;Two cases showed abnormal longitudinal section of the right atrium;42 LIVC fetuses showed an"S"sign on the coronal section of the inferior vena cava on ultrasound;28 cases of DIVC fetuses showed an"h"sign on the coronal section of the inferior vena cava on ultrasound.88 fetuses with IVC developmental abnormalities were associated with abnormalities in the cardiovascular system,skeletal system,urinary system,digestive system,respiratory system,and sensory system,respectively.There was a statistically significant overall difference in the proportion of isolated and combined intracardiac and extracardiac abnormalities in different types of IVC development(P<0.001);The ratio of isolated ECIVC to isolated DIVC and isolated LIVC,as well as the ratio of ECIVC with intracardiac abnormalities to LIVC and DIVC with intracardiac abnormalities,and it showed statistically significant differences(P<0.05).88 fetuses with abnormal IVC development,of which 5 were confirmed by induced labor;83 cases were followed up until 6 months after birth,and all underwent MRI and echocardiography examinations,which were consistent with prenatal diagnosis.Conclusion Fetal IVC developmental abnormalities have specificity in ultrasound images.Ultrasound can accurately identify whether there are concomitant abnormalities in the endocardial and endocardial structures.Analyzing the composition ratio of different types of IVC developmental abnormalities combined with abnormalities in the endocardial and endocardial structures can provide theoretical basis for clinical evaluation,prognosis,and management.Improving understanding and early diagnosis have important guiding value for clinical practice.