Echocardiographic evaluation of neurocardiac injury in patients with aneurysmal subarachnoid hemorrhage:a prospective study
Objective To discuss changes in cardiac function from early stage after aneurysmal subarachnoid hemorrhage(aSAH)to shortly later stage using echocardiography.Methods We prospectively studied 83 patients with aSAH in Beijing Hospital of Traditional Chinese Medicine from May 2018 to May 2023.These patients were divided into the highly positive cTnI group(cTnI≥0.3 ng/mL,n=25)and the mildly positive cTnI group(cTnI<0.3 ng/mL,n=58)according to cTnI level.Longitudinal strain and radial strain were acquired by strain echocardiography.Global longitudinal strain(GLS),the standard deviation of time-to-peak longitudinal strain from LV segments(LT-Dispersion),the standard deviation of time-to-peak radial strain from LV segments(RT-Dispersion)and the time-to-peak radial strain difference between LV anterior septum and posterior wall in left ventricular short axis view at papillary muscle level(APT)were measured and calculated.Results At early stage,LT-Dispersion,RT-Dispersion,APT and GLS in highly positive cTnI group were associated with more serious neurocardiac damage than others(P<0.05).Improvements(later stage vs early stage)of GLS,LT-Dispersion,RT-Dispersion and APT were more significantly better in the mildly positive cTnI group than in the highly positive cTnI group(P<0.05).Conclusion GLS and left ventricular regional discoordination measured by LT-Dispersion,RT-Dispersion and APT were significantly associated with neurocardiac injury severity after aSAH as reflected by elevated cTnI.Novel echocardiographic analysis to detect neurocardiac injury severity in patients with aSAH has promise for clinical utility.
国家科技期刊平台
NSTL
万方数据
维普
