高强度聚焦超声联合纳米颗粒在肿瘤治疗中的研究现状
Research status of high intensity focused ultrasound combined with nanoparticles in tumor treatment
陈宗桂 1潘桂洪 1管海辰1
作者信息
- 1. 湖南医药学院医学院,湖南 怀化 418000
- 折叠
摘要
在高强度聚焦超声消融肿瘤领域的研究中,理想的多模态多功能纳米诊疗剂不仅能够对感兴趣区域进行靶向治疗,还能特异性显影实现影像诊断的目的.二者联合应用可发挥协同作用,提高诊疗的精确性达到更好的治疗效果.本文就无机纳米颗粒、有机纳米颗粒、载有靶向基因的纳米颗粒、以化疗药物为核心的纳米颗粒在高强度聚焦超声消融肿瘤中的研究进展作一回顾.
Abstract
In the field of high-intensity focused ultrasound ablation of tumors,the ideal multi-mode and multi-functional nano-therapeutic agent is not only able to target the region of interest,but also achieve specific imaging diagnosis.The combined application can exert synergistic effects and achieve better therapeutic effects.This paper presents a review of the progress of research on inorganic nanoparticles,organic nanoparticles,nanoparticles containing targeted genes,and chemotherapeutic drug-centered nanoparticles in high intensity focused ultrasound ablated tumors.
关键词
高强度聚焦超声/靶向治疗/肿瘤消融Key words
high intensity focused ultrasound/targeted therapy/tumor ablation引用本文复制引用
基金项目
湖南省教育厅科学研究重点项目(22A0711)
湖南省教育厅一般项目(22C1183)
出版年
2024