Research progress and functional molecular imaging in patients with primary aldosteronism
Primary aldosteronism(PA)is a common cause of secondary hypertension and prones to cause damage to the end-organs,such as heart and kidney.Consequently,early diagnosis and adequate treatment can improve the prognosis of PA patients.Lateralization analysis of PA is a crucial stage in clinical practice.While adrenal vein sampling is recommended by guidelines as the gold standard for lateralization analysis of PA,the technique's invasiveness and technical difficulty limit its widespread application in regional hospitals.However,functional molecular imaging,which is easy to use and non-invasive,can offset the shortcomings of adrenal vein sampling in PA lateralization analysis,and can also provide powerful support in treatment decisions for PA.In order to provide a reference basis for lateralization analysis and subtype diagnosis of PA,we described the current state and progression of functional molecular imaging in PA both domestically and internationally.The physiological mechanisms,benefits,drawbacks and clinical applications of various adrenal functional molecular imaging techniques were also addressed in detail.Finally,we proposed the potential breakthrough and development direction of adrenal functional molecular imaging technology in the future.
万方数据
维普
