Clinical value of layer-specific quantification to predict the damage of myocardial function in patients with acute coronary syndrome by strain echocardiography
Objective To evaluate the layer-specific quantification for predicting the damage of myocardial function in patients with acute coronary syndrome(ACS)using strain echocardiography.Methods We prospectively studied 90 patients with ACS in Beijing Hospital of Traditional Chinese Medicine from January 2023 to November 2023,including 30 patients with unstable angina,30 patients with non-ST segment elevation myocardial infarction and 30 patients with ST segment elevation myocardial infarction according to ECG and serum troponin.Besides traditional echocardiographic parameters,subendocardial myocardium,medial myocardium and subepicardial myocardium were evaluated by layer-specific quantification strain.Results Lower absolute value of longitudinal strain and circumferential strain,longer longitudinal strain dispersion and circumferential strain dispersion with subendocardial myocardium in non-ST segment elevation myocardial infarction group.Longitudinal strain,circumferential strain,longer longitudinal strain dispersion and circumferential strain dispersion with medial and subepicardial myocardium in non-ST segment elevation myocardial infarction group were in normal reference interval.There was significant difference among three layers of myocardium(P<0.05).Conclusion Myocardial function of different layer of myocardium was evaluated by layer-specific quantification strain to predict myocardial damage,especially in patients with non-ST segment elevation myocardial infarction,and have more sensitivity and promises for clinical utility.