Clinical application value of color Doppler ultrasonography and MRI combined in diagnosis and staging of female early breast cancer
Objective To evaluate the clinical value of color Doppler ultrasonography and MRI in diagnosis and staging of early breast cancer.Methods A total of 1525 cases of women who underwent routine mammary gland examination in our hospital from August 2021 to October 2023 were collected,and 115 cases of them were found to be occupied by mammary glands.All the patients were admitted to hospital for operation.The clinical and related imaging data were analyzed.All patients were preoperatively performed color Doppler ultrasound and MRI examination,the pathologic result is taken as the gold standard of diagnosis,the detection rate of positive detection in the routine examination of female mammary glands by single color Dopplerultrasound,single MRI and different image examination methods combined with the two is observed,To compare the value of three kinds of examination methods in early diagnosis and staging of breast cancer.Results 115 patients underwent surgical resection and pathologic examination.123 lesions were detected,of which 67 were benign and 56 were malignant.Single color doppler ultrasound showed that 51 benign lesions and 16 misdiagnosed lesions.There were 46 malignant lesions and 10 missed lesions.MRI alone showed 61 benign lesions and 6 misdiagnosed lesions.There were 53 malignant lesions and 3 missed lesions.65 benign lesions were found and 2 were misdiagnosed.There were 54 malignant lesions and 2 missed lesions.The accuracy of single MRI and color Doppler ultrasound combined with MRI(93.50%,96.75%)was higher than that of single color Doppler ultrasound(78.86%,P<0.05).The sensitivity(96.43%),specificity(97.01%),positive predicted label(96.43%),negative predicted label(97.01%)of color Doppler ultrasonography combined with MRI were higher than those of color Doppler ultrasonography(82.14%,76.12%,74.19%,83.61%).There was no significant difference in sensitivity(94.64%),specificity(91.04%),positive predictive value(88.33%)and negative predictive value(96.83%)between MRI and color Doppler ultrasound(P>0.05).There was no significant difference between single color Doppler ultrasound,single MRI and the combined diagnosis of the two in different stages of breast cancer(P>0.05).Conclusion Single color Doppler ultrasonography and MRI have certain value in the diagnosis and differential diagnosis of benign and malignant breast lesions,and their combined application can effectively improve the accuracy:sensitivity and staging of early diagnosis of breast cancer.
color Doppler ultrasonographyMRIbreast cancerearly diagnosisperiod of application