Value of strain elastography combined with TIRADS in differential diagnosis of benign and malignant thyroid nodules
Objective To investigate the value of strain elastography combined with thyroid imaging reporting and data system(TIRADS)in the differential diagnosis of benign and malignant thyroid nodules.Methods A total of 82 patients with thyroid nodules who were treated in the Third Affiliated Hospital of Xuzhou Medical University from January 2020 to January 2023 were selected.All patients underwent strain ultrasound elastography and TIRADS score.With pathological examination as the gold standard for diagnosis,the subjects were divided into malignant group(n=8)and benign group(n=74).Logistic regression model was used to screen the independent predictors of malignant thyroid nodules.ROC curve was used to evaluate the efficacy of strain elastography,elastic strain ratio(SR),TIRADS score and their combination in the diagnosis of benign and malignant thyroid nodules.Results There were significant differences in strain ultrasound elastography score,SR and TIRADS score between the two groups(P<0.05).Multivariate Logistic regression analysis showed that strain ultrasound elastography score,SR and TIRADS score were independent predictors of malignant thyroid nodules,with OR values of 1.675,1.550 and 1.476,respectively(P<0.05).ROC curve analysis showed that the area under the curve of strain ultrasound elastography score,SR,TIRADS score and the combination of the three in the diagnosis of malignant thyroid nodules were 0.794,0.919,0.875,0.994,respectively,and the combination of the three had the highest diagnostic value(P<0.001).Conclusion Strain elastography and TIRADS have certain value in the differential diagnosis of benign and malignant thyroid nodules.The combination of the two methods can improve the diagnostic efficiency.