Predictive value of multi-slice spiral CT for invasive lung adenocarcinoma in the latest international association for the study of lung cancer tertiary system
Objective To investigate the predictive value of multi-slice spiral CT(MSCT)for invasive lung adenocarcinoma with the new version of the three-stage stratification system.Methods The clinical,MSCT and pathological data of 120 patients with pathologically confirmed invasive lung adenocarcinoma admitted to the Cardiothoracic Surgical Ward of the First Affiliated Hospital of Jiamusi University from July 2022 to September 2023 were retrospectively collected,and the cases were classified into the highly differentiated group(predominantly adherent type,and the high-grade component<20%,n=17),the moderately differentiated group(predominantly acinar/nipple type,and the high-grade component<20%,n=61),and the low-differentiated group(any subtype and high-grade component≥20%,n=42).The relationship between MSCT signs and the degree of differentiation in the three groups was analyzed and compared among the three groups of patients.Results The results of univariate analysis showed that there was no statistically significant difference in age,gender and smoking history among the three groups(P>0.05).The differences in diameter,lesion type,lobulated sign,spinous process sign,air-containing cavities,air bronchogram sign,obstructive emphysema,changes of vessels,and lymphadenectasis between the low-differentiated group and the moderately-and highly differentiated groups were statistically significant(P<0.05),and the differences in the number and shape of the lesions,and the spicule sign,calcification and pleural traction sign were not statistically significant(P>0.05).The results of multivariate ordered Logistic regression analysis showed that diameter(OR=1.093,P=0.001)and lesion type(OR=0.308,P=0.033)were risk factors for low-differentiated in the latest IASLC tertiary stratification system for lung adenocarcinoma.Conclusion MSCT has a predictive value for the latest IASLC tertiary stratification system of invasive lung adenocarcinoma,which can guide the clinic to formulate a treatment plan for patients in line with individualization.
万方数据
维普
