Prenatal diagnosis and prognostic analysis of fetuses with vena cava anomalies observed from multiple perspectives
Objective To observe the prenatal diagnosis and prognosis analysis of vena cava anomalies fetuses from multiple perspectives,and to provide experience for integrated maternal-fetal management.Methods A total of 105 fetuses born in the first affiliated Hospital of University of Science and Technology of China from 2021 to 2023 were retrospectively analyzed.According to the abnormal development of vena cava,the fetuses were divided into two groups:abnormal vena cava group(n=51)and normal vena cava group(n=54).The routine prenatal data and pregnancy outcome of the two groups were analyzed to explore the influencing factors of adverse pregnancy outcome of abnormal vena cava.Results There was significant difference in adverse pregnancy outcome between abnormal vena cava fetus and normal fetus(P<0.05).The incidence of adverse pregnancy outcome of abnormal vena cava fetus was higher than that of normal fetus.There was significant difference in adverse pregnancy outcome among isolated vena cava abnormal fetus,intracardiac abnormal fetus and extracardiac abnormal fetus(P<0.05).There was significant difference in adverse pregnancy outcome between isolated vena cava abnormal fetus and intracardiac abnormal fetus(P<0.05).There was no significant difference in adverse pregnancy outcome between isolated vena cava abnormal fetus and extracardiac abnormal fetus,extracardiac abnormal fetus and intracardiac abnormal fetus(P>0.05).There was no significant correlation between maternal age,common complications during pregnancy and adverse pregnancy outcome of abnormal vena cava fetus(P>0.05).Intracardiac malformation was an important influencing factor of adverse pregnancy outcome of abnormal vena cava fetus(P<0.05).Conclusion The adverse pregnancy outcomes of fetuses with vena cava anomalies differed from those of normal fetuses,and the combination of intracardiac malformations was a risk factor for the adverse pregnancy outcomes of fetuses with vena cava anomalies.