18 F-FDG PET/CT imaging has diagnostic value in dermatomyositis accompanied by malignant tumors
Objective To explore the imaging characteristics of 18F-FDG PET/CT in patients with dermatomyositis accompanied by malignant tumors,with the aim of enhancing understanding of this disease.Methods A retrospective analysis was conducted on 14 patients diagnosed with dermatomyositis and malignant tumors through pathology,spanning from April 2018 to March 2023.The degree of muscle uptake throughout the body was analyzed by manually delineating regions of interest.Meanwhile,a normal control group(n=14)was established,and the muscle uptake values of the control group were measured.Differences in muscle uptake values between the two groups were then compared.Results Among the 14 patients with dermatomyositis,there were 4 cases of gastric cancer,3 cases of ovarian cancer,2 cases of lymphoma,1 case each of lung cancer,esophageal cancer,nasopharyngeal cancer,and breast cancer,as well as 1 case of poorly differentiated adenocarcinoma of unknown origin.The average muscle uptake value of the patients with dermatomyositis was 3.5±1.8,which was significantly higher than the average value of 1.3±0.1 in the control group,and the difference was statistically significant(P<0.001).Conclusion 18F-FDG PET/CT imaging not only enables the assessment of disease activity through the diffuse uptake degree of muscles and provide a basis for biopsy of the lesions,but also facilitates the staging and evaluation of accompanying malignant tumors,offering significant imaging reference value for clinicians in further precise diagnosis and treatment.
国家科技期刊平台
NSTL
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