Umbilical artery blood flow color Doppler ultrasound parameters can evaluate fetal growth restriction
Objective To explore the diagnostic value of umbilical artery blood flow color Doppler ultrasound parameters on fetal growth restriction(FGR).Methods Fifty pregnant women with FGR diagnosed in the third trimester of pregnancy in the Department of Obstetrics and Gynecology,Suzhou Hospital Affiliated to Nanjing University School of Medicine from January 2022 to June 2024 were retrospectively analyzed as FGR group,and another 50 pregnant women with normal fetal intrauterine development during the same period were selected as control group.Fetal umbilical artery blood flow indicators were diagnosed by color Doppler ultrasound.The baseline data and clinical indicators of pregnant women and fetuses in FGR group and control group were compared.The fetal umbilical artery blood flow indicators[pulsatility index(PI),resistance index(RI),end-systolic velocity(PSV),end-diastolic velocity(EDV),end-systolic/end-diastolic velocity(S/D)]were compared between FGR group and control group.According to the pregnancy outcomes,they were divided into good group(n=14)and poor group(n=36).The PI,RI,PSV,EDV and S/D of fetal umbilical artery were compared between good group and poor group.Binary logistics equation was used to analyze the related influencing factors affecting the prognosis of FGR.ROC curve was drawn and the area under the curve(AUC),sensitivity and specificity were calculated to evaluate the diagnostic value of umbilical artery blood flow color Doppler ultrasound parameters on FGR.Results The proportion of normal birth in FGR group was significantly higher than that in control group(P<0.05)while the fetal body weight,Apgar,head circumference,double parietal diameter and femoral diameter were significantly lower than those in control group(P<0.05).The PI,RI and S/D in FGR group were significantly higher(P<0.05)while the EDV was significantly lower than that in control group(P<0.05),but there was no statistical significance in PSV between groups(P>0.05).PI,RI and S/D in poor group were significantly higher than those in good group(P<0.05)while EDV was significantly lower(P<0.05),but there was no statistical difference in PSV between both groups(P>0.05).Umbilical artery PI,RI,S/D and EDV were correlated with adverse pregnancy prognosis(P<0.05).When the critical values of PI,RI and S/D were 1.365,0.679,3.115,13.638,the AUCs were 0.704,0.925,0.760,0.734,respectively,and the AUC of combined diagnosis of adverse pregnancy outcomes was 0.980,indicating a higher value of combined diagnosis.Conclusion Umbilical artery blood flow color Doppler ultrasound parameters have certain evaluated value for the diagnosis of FGR,which can be used as a reference for clinical diagnosis.
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