The role of serum D-D,PCT combined with CRP in the assessment of disease condition and prognosis of children with mycoplasma pneumoniae pneumonia
Objective To analyze the effects of serum D-dimer(D-D),procalcitonin(PCT)combined with C-reactive protein(CRP)in the assessment of disease condition and prognosis of children with mycoplasma pneumoniae pneumonia(MPP).Methods A total of 151 children with MPP admitted to Xu-ancheng People's Hospital from September 2021 to May 2022 were selected as the study objects and were di-vided into the mild group(104 cases)and the severe group(47 cases)according to the severity of the disease.The levels of serum D-D,PCT and CRP in children with different severity of the disease were compared.The correlation between serum D-D,PCT and CRP levels and CPIS score was analyzed.The levels of serum D-D,PCT and CRP in different prognosis of children were compared,and the value of single or combined D-D,PCT and CRP in the prognosis of MMP children was analyzed.Results The levels of D-D,PCT,CRP and CPIS in the severe group were significantly higher than those in the mild group,and the difference was statisti-cally significant(P<0.05).Serum D-D,PCT and CRP levels were positively correlated with CPIS score(P<0.05).Serum D-D,PCT and CRP levels in the poor prognosis group were significantly higher than those in the good prognosis group,and the difference was statistically significant(P<0.05).The ROC results showed that the sensitivity and specificity of D-D + PCT + CRP were 0.932 and 0.901 respectively,the AUC=0.856(95%CI:0.846～0.935),which was higher than that of D-D,PCT and CRP alone(P<0.05).Conclusion Serum D-D,PCT and CRP are closely related to the progression of MPP and can be used as important indica-tors for prognosis assessment.The combination of the three is more conducive to determining the severity and prognosis of children with MPP.
NETL
NSTL
万方数据
维普
