Predictive value of preoperative FDP level on slow/no reflow during PCI of patients with acute myocardial infarction
Objective To study the predictive value of preoperative fibrinogen degradation prod-uct(FDP)on slow/no reflow during percutaneous coronary intervention(PCI)of patients with acute myocar-dial infarction(AMI).Methods AMI patients who received emergency PCI in Zhengzhou Seventh People's Hospital from January 2021 to October 2022 were divided into the slow/no reflow group and the control group according to intraoperative slow/no reflow.Preoperative biochemical parameters,FDP,D-dimer(D-D),interleukin-6(IL-6),interleukin-17(IL-17)were detected,the differences of each indicator between the 2 groups were compared,the influencing factors of slow/no reflow were analyzed by the logistic regression model and the predictors of slow/no reflow were analyzed by the ROC curve.Results There was no signifi-cant difference in biochemical parameters between the slow/no reflow group and the control group(P>0.05).Preoperative FDP,D-D,IL-6 and IL-17 in the slow/no reflux group were higher than those in the control group(t=7.468,6.070,16.668,8.182,P<0.05).Preoperative FDP and D-D levels positively correlated with IL-6 and IL-17 in the slow/no reflow group(P<0.05).FDP,D-D,IL-6 and IL-17 were influencing factors of slow/no reflow(P<0.05).FDP and D-D had good predictive value of slow/no reflow during PCI(P<0.05).Conclusion The increased preoperative FDP is associated with slow/no reflow during emergency PCI of AMI patients,and FDP combined with D-D test has predictive value for slow/no reflow.
NETL
NSTL
万方数据
维普
