Correlation between clinical manifestations and quantitative values of MRI and DTI in pa-tients with cervical spondylotic myelopathy
Objective To explore the correlation between clinical manifestations and quantitative values of magnetic resonance imaging(MRI)and diffusion tensor imaging(DTI)in patients with cervical spondylotic myelopathy(CSM).Methods 65 patients with CSM in Hebei China Petroleum Central Hospital from January 2020 to December 2022 were selected as the research subjects.According to Japanese Orthopedic Association(JOA)score,the patients were divided into the mild group,the moderate group and the severe group.MRI and DTI were performed on all patients.MRI manifestations of spinal cord at the narrowest level of the lesion segment,as well as DTI parameters[apparent diffusion coefficient(ADC),fractional anisotropy(FA)]and eigenvalues(λ1 value,λ2 value,λ3 value)were analyzed among the groups.Pearson correlation was used to analyze the correlation between ADC,FA value and eigenvalues and JOA score.Results The proportion of high signal on MRI T2WI in the severe group was higher than that in the moderate group and the mild group(χ2=35.033,P<0.05),but there was no statistical difference in the distribution of MRI signal mani-festation between the moderate group and the mild group(χ2=0.931,P>0.05).Comparison of ADC values of diseased segments in three groups:severe group>moderate group>mild group(F=40.042,P<0.05).Com-parison of FA values:severe group<moderate group<mild group,the differences between groups were statis-tically significant(F=33.145,P<0.05).There was no statistical significance in λ1 value of lesion segment among the three groups(F=0.344,P>0.05),and the λ2 value and λ3 value were shown as severe group>mod-erate group>mild group,and the differences between groups were statistically significant(F=25.296/62.994,P<0.05).Pearson correlation analysis showed that the ADC value was negatively correlated with the JOA score(P<0.05),and the FA value was positively correlated with the JOA score(P<0.05).Conclusion Routine MRI scans and DTI quantitative values can reflect the degree of spinal cord segment damage in patients with CSM,and the ADC value and FA value are linearly related to the severity of the patient's clinical symptoms.
NETL
NSTL
万方数据
维普
