The effect of laparoscopic myomectomy combined with uterine artery ascending branch occlusion on sexual function,recurrence,and FSH,E2,and LH levels in patients with uterine fibroids
Objective To study the effects of laparoscopic myomectomy combined with uterine artery ascending branch occlusion on sexual function,recurrence and follicle stimulating hormone(FSH),estradiol(E2)and luteinizing hormone(LH)levels in patients with uterine fibroids. Methods A total of 116 patients with uterine fibroids admitted to the First Affiliated Hospital of Zhengzhou University from May 2020 to May 2021 were selected as the research subjects. They were divided into two groups based on the treatment plan:the control group(n=56,treated with LM)and the observation group(n=60,treated with LM combined with uterine artery ascending branch occlusion)according to the treatment plan. The perioperative indicators were compared between the two groups. Additionally,sex hormones(FSH,E2 and LH),sexual function,uterine fibroid residual rate,and recurrence rate were also compared. Results The operation time of the observation group was longer than that of the control group. However,the intraoperative blood loss was less in the observation group compared to the control group. Additionally,the observation group had shorter postoperative exhaust,gastrointestinal function repair and hospitalization time compared to the control group,with statistically significant differences(P<0.05). Before the operation,there was no statistically significant difference in the levels of FSH,E2 and LH between the two groups(P>0.05). However,at 3 months after the opration, FSH and LH levels were higher than before the operation in both groups. The observation group had higher levels of FSH,and LH,while E2 levels were lower in the observation group. Those differences were statistically significant(P<0.05). At 6 months after operation,there was no significant difference in the levels of FSH,E2 and LH between the two groups(P>0.05). Before the operation,there was no statistically significant difference in sexual function scores between the two groups. However,at 6 months after the operation,the sexual function scores improved in both groups. There was no statistically significant difference between the two groups (P>0.05). The residual rate of uterine fibroids in the observation group was 0.00％,while was significantly lower than the control group's rate of 21.43％. Additionally,the recurrence rate in the observation group was 10.71％, significantly lower than the control group ' s rate of 3.33％. These differences were statistically significant(P<0.05). Conclusion LM combined with uterine artery ascending branch occlusion has a temporary impact on ovarian function in patients with uterine fibroids. However,over time,ovarian function gradually returns to its preoperative level. Furthermore,this procedure has shown better results in improving sexual function and reducing the residual rate and recurrence rate of uterine fibroids.
万方数据
维普
