摘要
随着人们对肠道菌群不断深入的探究,已知肠道菌群与肥胖、糖尿病、焦虑、忧郁、神经退行性疾病等多种疾病相关.其中,研究者们发现肠道菌群可以影响认知功能,"微生物-肠-脑轴"逐渐成为研究热点,肠道菌群与中枢神经系统之间的交流涉及免疫、神经、内分泌等复杂机制.本文旨在阐明肠道菌群对认知功能的影响及其机制,为认知功能障碍的治疗提供新思路.
Abstract
With the continued exploration of gut microbiota,it is known that gut microbiota is as-sociated with various diseases such as obesity,diabetes,anxiety,depression,and neurodegenerative diseases. Moreover,researchers have found that gut microbiota can affect cognitive function,and the"microbiota-gut-brain axis"has gradually become a hot spot for research. The communication network between gut microbiota and the central nervous system is complex and includes the immune system,nervous system,endocrine sys-tem,and so onmore. This paper review aims to elucidate the effect of gut microbiota on cognitive function and its mechanism and to provide new ideas for the treatment of cognitive dysfunction.
基金项目
中国博士后科学基金面上项目(2022M710492)
常州市卫生健康青苗人才培养工程项目(CZQM2020078)
常州市应用基础研究项目(CJ20210111)
维普
万方数据