Prognostic effect of GBS,chlamydia combined with Ureaplasma urealyticum detection on pregnancy outcomes in patients with premature rupture of fetal membranes
Objective To investigate the predictive effect of Group B streptococcus(GBS),chla-mydia,and Ureaplasma urealyticum(UU)detection on pregnancy outcomes in patients with premature rup-ture of fetal membranes. Methods A total of 168 women with premature rupture of membranes admitted to Xinhua Hospital,affiliated with Shanghai Jiao Tong University School of Medicine,from February 2021 to January 2023 were selected as the observation group. Another 165 pregnant women with normal results were se-lected as the control group. The positive rates of GBS,chlamydia and UU were compared between the two groups. The predictive results of GBS ,chlamydia and UU on adverse pregnancy outcome were analyzed. Results The positive rates of GBS,chlamydia and UU in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05). There were 122 GBS negative cases and 46 GBS positive cases. The incidence of adverse pregnancy outcomes in GBS positive pregnant women with premature rupture of membranes was higher than that in control group ,and the differences were statistical-ly significant(P<0.05). There were 128 cases chlamydia negative,40 cases incidence of adverse pregnancy outcome in chlamydia positive pregnant women with premature rupture of membranes was higher than that in the control group,and the differences were statistically significant(P<0.05). There were 117 UU negative cas-es and 51 UU positive cases. The incidence of adverse pregnancy outcomes in UU-positive pregnant women with premature rupture of membranes was higher than that in the control group ,and the differences were statis-tically significant(P<0.05). Among 168 pregnant women with premature rupture of membranes,117 cases were negative for GBS,chlamydia and UU,11 cases were positive for one or two of GBS,chlamydia and UU,and 40 cases were positive for GBS,chlamydia and UU;GBS,chlamydia and UU were all positive. The incidence of adverse pregnancy outcomes in pregnant women with GBS ,chlamydia and UU was higher than those with single or two infections and negative premature rupture of membranes ,and the differences were sta-tistically significant(P<0.05). Conclusion The positive rates of GBS,chlamydia and UU in pregnant wom-en with premature rupture of membranes are higher than those in normal pregnant women ,and the combined detection of the three can more accurately predict maternal and fetal adverse outcomes.
Group B StreptococcusChlamydiaUreaplasma urealyticumPremature rupture of membranesPregnancy outcome