首页|GBS、衣原体联合解脲支原体检测对胎膜早破患者妊娠结局的预测作用

GBS、衣原体联合解脲支原体检测对胎膜早破患者妊娠结局的预测作用

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目的 研究B族链球菌(GBS)、衣原体联合解脲支原体(UU)检测对胎膜早破患者妊娠结局的预测作用.方法 选取上海交通大学医学院附属新华医院2021年2月至2023年1月收治的胎膜早破产妇168例为观察组,另选取同期进行孕检且结果正常的165名孕妇为对照组.对比两组GBS、衣原体、UU阳性率;分析GBS、衣原体、UU单一检测对观察组不良妊娠结局的预测结果;分析GBS、衣原体、UU三者联合对观察组孕妇不良妊娠结局的预测结果.结果 观察组GBS阳性率、衣原体阳性率、UU阳性率均比对照组高,差异均有统计学意义(P<0.05).GBS阴性122例,GBS阳性46例,GBS阳性胎膜早破孕妇不良妊娠结局发生率比对照组高,差异有统计学意义(P<0.05).衣原体阴性128例,衣原体阳性40例,衣原体阳性胎膜早破孕妇不良妊娠结局发生率比对照组高,差异有统计学意义(P<0.05).UU阴性117例,UU阳性51例,UU阳性胎膜早破孕妇不良妊娠结局发生率比对照组高,差异有统计学意义(P<0.05).168例胎膜早破孕妇中,GBS、衣原体和UU均为阴性117例,GBS、衣原体和UU为单一一个或两个为阳性11例,GBS、衣原体和UU均为阳性40例;GBS、衣原体和UU均为阳性胎膜早破孕妇不良妊娠结局发生率均比单一或两个感染及阴性胎膜早破孕妇高,差异有统计学意义(P<0.05).结论 胎膜早破孕妇的GBS、衣原体和UU阳性率均高于正常妊娠孕妇,且GBS、衣原体和UU联合检测可更准确地预测母体和胎儿不良结局.
Prognostic effect of GBS,chlamydia combined with Ureaplasma urealyticum detection on pregnancy outcomes in patients with premature rupture of fetal membranes
Objective To investigate the predictive effect of Group B streptococcus(GBS),chla-mydia,and Ureaplasma urealyticum(UU)detection on pregnancy outcomes in patients with premature rup-ture of fetal membranes. Methods A total of 168 women with premature rupture of membranes admitted to Xinhua Hospital,affiliated with Shanghai Jiao Tong University School of Medicine,from February 2021 to January 2023 were selected as the observation group. Another 165 pregnant women with normal results were se-lected as the control group. The positive rates of GBS,chlamydia and UU were compared between the two groups. The predictive results of GBS ,chlamydia and UU on adverse pregnancy outcome were analyzed. Results The positive rates of GBS,chlamydia and UU in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05). There were 122 GBS negative cases and 46 GBS positive cases. The incidence of adverse pregnancy outcomes in GBS positive pregnant women with premature rupture of membranes was higher than that in control group ,and the differences were statistical-ly significant(P<0.05). There were 128 cases chlamydia negative,40 cases incidence of adverse pregnancy outcome in chlamydia positive pregnant women with premature rupture of membranes was higher than that in the control group,and the differences were statistically significant(P<0.05). There were 117 UU negative cas-es and 51 UU positive cases. The incidence of adverse pregnancy outcomes in UU-positive pregnant women with premature rupture of membranes was higher than that in the control group ,and the differences were statis-tically significant(P<0.05). Among 168 pregnant women with premature rupture of membranes,117 cases were negative for GBS,chlamydia and UU,11 cases were positive for one or two of GBS,chlamydia and UU,and 40 cases were positive for GBS,chlamydia and UU;GBS,chlamydia and UU were all positive. The incidence of adverse pregnancy outcomes in pregnant women with GBS ,chlamydia and UU was higher than those with single or two infections and negative premature rupture of membranes ,and the differences were sta-tistically significant(P<0.05). Conclusion The positive rates of GBS,chlamydia and UU in pregnant wom-en with premature rupture of membranes are higher than those in normal pregnant women ,and the combined detection of the three can more accurately predict maternal and fetal adverse outcomes.

Group B StreptococcusChlamydiaUreaplasma urealyticumPremature rupture of membranesPregnancy outcome

罗婷婷、施云、张丽

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上海交通大学医学院附属新华医院产房,上海200092

B族链球菌 衣原体 解脲支原体 胎膜早破 妊娠结局

国家自然科学基金

82272641

2024

分子诊断与治疗杂志
中山大学

分子诊断与治疗杂志

CSTPCD
影响因子:0.65
ISSN:1674-6929
年,卷(期):2024.16(3)
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