红细胞分布宽度/白蛋白比值对重症社区获得性肺炎不良结局预测价值
Analysis of predictive value of red cell distribution width/albumin ratio on adverse outcome for patients with severe community-acquired pneumonia
李川 1唐伟伟 2方长太1
作者信息
- 1. 安庆市立医院重症医学科,安徽,安庆 246003
- 2. 安庆市立医院急诊科,安徽,安庆 246003
- 折叠
摘要
目的 探讨红细胞分布宽度/白蛋白(RDW/ALB)比值对重症社区获得性肺炎(sCAP)不良结局的预测价值.方法 分析107例sCAP患者的临床资料,根据30d预后情况分为预后不良组和预后良好组.采用单因素和多因素Logistic回归分析,揭示预后的影响因素.采用受试者特征工作(ROC)曲线分析RDW/ALB比值预测预后的能力.结果 sCAP患者预后不良组RDW/ALB比值的中位数显著高于预后良好组(P<0.05),RDW/ALB比值越高,30 d预后不良发生率越高(OR=1.155,95%CI:1.007～2.430,P<0.05).计算RDW/ALB比值曲线下面积(AUC)为0.761(95%CI:0.665～0.857),高于肺炎严重程度指数(PSI)评分的0.740(95%CI:0.643～0.837)(P<0.05).当RDW/ALB比值与PSI评分结合时,AUC值增加到0.817(95%CI:0.736～0.899),高于PSI评分或单独的RDW/ALB比值(P<0.05).结论 RDW/ALB比值具有较好预测重症社区获得性肺炎不良结局的价值.
Abstract
Objective To investigate the predictive value of red blood cell distribution width/albu-min ratio(RDW/ALB)on adverse outcome for patients with severe community-acquired pneumonia(sCAP).Methods Clinical data from 107 patients with sCAP were retrospectively analyzed and divided into two groups:a poor prognosis group and a good prognosis group based on their 30-day prognosis.Univariate and mul-tivariate logistic regression analyses was used to identify the prognostic factors.Receiver operating characteristic(ROC)curve was used to assess the predictive ability of the RDW/ALB ratio for prognosis.Results The medi-an RDW/ALB ratio of sCAP patients with a poor prognosis was significantly higher than that of the good progno-sis group(P<0.05).A higher RDW/ALB ratio was associated with a higher incidence of 30-day poor prognosis(OR=1.155,95%CI:1.007～2.430,P<0.05).Meanwhile,the area under the curve(AUC)of the RDW/ALB ratio was 0.761(95%CI:0.665～0.857),which was higher than the AUC of 0.740(95%CI:0.643～0.837)in the pneumonia severity index(PSI)(P<0.05).When the RDW/ALB ratio was combined with the PSI score,the AUC increased to 0.817(95%CI:0.736～0.899),which was higher than either the PSI score or RDW/ALB ratio alone(P<0.05).Conclusion The RDW/ALB ratio has great predictive value for postoperative adverse out-comes in patients with severe community-acquired pneumonia.
关键词
重症社区获得性肺炎/白蛋白/红细胞分布宽度/红细胞分布宽度/白蛋白比值/肺炎严重程度指数Key words
Severe community-acquired pneumonia/Albumin/Red cell distribution width/Red blood cell distribution width/albumin/Pneumonia severity index引用本文复制引用
基金项目
安徽省医学会急诊医学分会急诊临床研究项目(2021)(Ky2021016)
出版年
2024
NETL
NSTL
万方数据