Application of Lactate,Albumin and Its Ratio in High Mortality of ICU Diseases
Lactate(Lac)is an important product of cells produced by anaerobic metabolism.Lac levels will gradually increase during insufficient tissue perfusion and hypoxia,which is often clinically related to the poor prognosis of patients.Albumin(Alb)is synthesized by the liver.Its main role is to maintain plasma colloid osmotic pressure and evaluate its nutritional status.At present,the studies of serum Lac,Alb and their ratio are mostly focused on Intensive Care Units(ICU)high mortality diseases such as severe pneumonia,sep-sis and acute kidney injury.The results of the three studies are all related to the evolution of the disease and can be used as effective indicators to assist diagnosis and treatment.However,Lac,Alb and its ratios have differ-ent regulatory mechanisms and clinical applications in the diagnosis,prognosis evaluation,disease monitoring and other aspects of different diseases.This paper reads the relevant literature at home and abroad,and summa-rizes the latest research results of Lac,Alb and their ratio in clinical diseases,in order to provide reference for the diagnosis and prognosis of high fatal diseases in ICU.
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