Effects of Shenxiong glucose injection combined with Daglipzin on renal function and urinary protein in patients with early type 2 diabetic nephropathy
Objective To investigate the effects of Shenxiong glucose injection combined with Daglipzin on renal function and urinary protein in patients with early type 2 diabetes mellitus(T2DM).Meth-ods A total of 100 patients with early T2DM nephropathy treated at Linquan County People's Hospital from January 2021 to January 2023 were selected as study subjects.They were divided into two groups based on treatment methods:thestudy group(Shenqin glucose injection combined with daglizin treatment,n=57)and the control group(daglizin treatment,n=43).Renal function,urinary protein levels,clinical efficacy,and ad-verse reactions were compared between the two groups.Results After treatment,the levels of blood urea ni-trogen(BUN)and serum creatinine(Scr)in the study group were lower than those in the control group,and the differences were statistically significant(t=3.376,3.010,P<0.05).After treatment,the creatinine clear-ance(Ccr)and glomerular filtration rate(eGFR)in the study group were higher than those in the control group,and the differences were statistically significant(t=2.377,2.802,P<0.05).After treatment,the levels of urinary microalbumin(UALB),urinary microalbumin to creatinine ratio(UACR)of the study group were lower than those of the control group,and the differences were statistically significant(t=6.728,4.994,P<0.05).The effective rate of the study group was higher than that of the control group,and the differences were statistically significant(χ2=5.697,P<0.05).There was no significant difference in the incidence of adverse re-actions between the two groups(χ2=0.018,P>0.05).Conclusion Shenxiong glucose injection,when com-bined with daglizin can improve renal function and reduce urinary protein in patients with early T2DM nephrop-athy.This treatment has been shown to have a positive therapeutic effect.
Shenxiong glucose injectionDaglizinType 2 diabetic nephropathyKidney func-tionUrinary protein
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