The value of transvaginal ultrasound combined with serum CEA and AFP detection in the diagnosis of endometriotic cysts
Objective To explore the application value of vaginal ultrasound combined with serum carcinoembryonic antigen(CEA)and alpha fetoprotein(AFP)detection in the diagnosis of endometriotic cysts.Methods A total of 102 patients with suspected EIC who were diagnosed at Taihe County People's Hospital in Anhui Province were selected as the research subjects.Vaginal ultrasound examinations were conducted,and se-rum CEA and AFP levels were measured.ROC curves were used to analyze the diagnostic value of serum CEA and AFP levels for EIC.The four-fold table method was used to analyze the diagnostic value of the combination of three factors for EIC.Results The serum CEA and AFP levels in patients with positive endometriotic cysts were significantly higher than those in the negative group,the difference was statistically significant(P<0.05).The serum CEA and AFP levels in patients with endometriotic cysts with r-AFS staging of stage Ⅲ～Ⅳ were sig-nificantly higher than those in patients with stage Ⅰ～Ⅱ positive cysts,the difference was statistically signifi-cant(P<0.05).The area under the ROC curve for serum CEA and AFP levels in diagnosing EIC was 0.813 and 0.778.Transvaginal ultrasound examination showed 72 cases of positive EIC and 30 cases of negative EIC.The sensitivity and accuracy of vaginal ultrasound combined with serum CEA and AFP were significantly higher than those of the three alone(P<0.05),with high consistency between the combined diagnosis and the gold standard diagnosis(Kappa=0.703,P<0.001).Conclusion Vaginal ultrasound combined with serum CEA and AFP detection has a high application value in diagnosing endometriotic cysts.This combination can enhance the sensitivity and accuracy of diagnosis,ultimately reducing the rate of missed diagnoses.
NETL
NSTL
万方数据
